منابع مشابه
Polypharmacy in pediatric patients and opportunities for pharmacists’ involvement
Rates of chronic conditions among pediatrics have been steadily increasing and medications used to treat these conditions have also shown a proportional increase. Most clinical trials focus on the safety of solitary medications in adult patients. However, data from these trials are often times extrapolated for use in pediatric patients who have different pharmacokinetic processes and physical p...
متن کاملRational polypharmacy
The development of assays for plasma antiepileptic drug concentrations has led to the discovery of many pharmacokinetic interactions, some causing drug intoxication and others resulting in ineffective drug concentrations. In the 1970s, a number of epileptologists began to argue that single drug therapy was desirable in the treatment of epilepsy and this has become the accepted policy when initi...
متن کاملPolypharmacy vs. Deprescribing
Usually, the elderly and patients with chronic diseases visit several doctors and are supposed to take multiple medications. The multiplicity of medications is called polypharmacy and it may cause side effects, drug interactions and other helth issues for the patient, and it might go as far as the patient might need to go to the hospital and be admitted in ICU, or even further and be the cause ...
متن کاملThe depth, duration, and degree of outpatient pediatric polypharmacy in Colorado fee-for-service Medicaid patients.
BACKGROUND AND OBJECTIVES Outpatient pediatric polypharmacy is poorly characterized. Identification of at-risk populations has clinical implications for pharmacy case management programs. We described the degree of exposure to polypharmacy using parameters of depth (concurrent medication count) and duration, reported commonly dispensed medications and exposure to three example potential drug-dr...
متن کاملUnnecessary polypharmacy for epilepsy.
A retrospective survey of 50 adult epileptic outpatients who were taking two anticonvulsants drugs showed that seizure control had improved in the six months after the introduction of the second drug in only 36%. When blood concentrations of the two anticonvulsants were subsequently measured improvement in seizure control was found to be significantly related to the presence of optimum blood co...
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ژورنال
عنوان ژورنال: Canadian Journal of Cardiology
سال: 2008
ISSN: 0828-282X
DOI: 10.1016/s0828-282x(08)70209-5